Jimmy Holder

Jimmy Holder is a physician-scientist and child neurologist. Dr. Holder obtained his MD and PhD from the University of Texas Southwestern in 2005. He then pursued a postdoctoral fellowship in neurogenetics at the University of California, San Francisco from 2005 to 2007. Beginning in 2007, he continued his clinical training in pediatrics and child neurology at Baylor College of Medicine, culminating in a research fellowship with Huda Zoghbi. He currently serves as an Investigator in the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, as well as an Associate Professor of Pediatrics and Neurology at Baylor College of Medicine.

In 2013, he opened the Developmental Synaptopathy Clinic at Texas Children’s Hospital initially to care for children with Phelan-McDermid syndrome but later expanded to include SYNGAP1-related disorder, STXBP1 developmental and epileptic encephalopathy, and Shine syndrome, among others.

He has served as a Principal Investigator on R01 program project grants and site investigator for both multi-site NIH projects, as well as industry-sponsored therapeutic trials. His scientific focus is translating bench discoveries to clinical applications for neurodevelopmental disorders.